Drosophila as a model for the identification of genes causing adult human heart disease.
Published in Proceedings of the National Academy of Sciences of the United States of America
Drosophila melanogaster genetics provides the advantage of molecularly defined P-element insertions and deletions that span the entire genome. Although Drosophila has been extensively used as a model system to study heart development, it has not been used to dissect the genetics of adult human heart disease because of an inability to phenotype the ...
